While an acute decrease in brain serotonin may have few effects on social behaviour, a longer-term increase in serotonin in individuals at risk for depression improves mood and alters social behaviour. This Thursday, February 4, 2016, Koen Hogenelst defends his dissertation, in which he explains the relevance of his research findings for the effectiveness of serotonergic medications for depression.
You may know an irritable person. But if he becomes friendlier towards you, then you will become friendlier towards him, right? In other words, positive changes in how people interact with others are ultimately good for them, too. This idea underlies a new theory on how antidepressants work.